Surgery for Liver Cancer

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Surgery for Liver Cancer

Liver cancer is a serious condition and for many patients, surgery offers a chance at long-term survival. If you or a loved one has been diagnosed with liver cancer, understanding what liver surgery involves can help you make confident and informed decisions about your care.

What is Liver Cancer Surgery?

What is Liver Cancer Surgery?

Liver cancer surgery involves the removal of cancerous tissue from the liver. This can range from excising a portion of the liver (known as a resection) to replacing the entire liver through transplantation.

The liver can regenerate, so it’s possible to remove large sections safely in many cases, so long as the remaining liver tissue is adequate in volume and healthy enough to continue functioning. Surgical treatment is usually most effective in the early stages of liver cancer and when the disease is confined to the liver.

What are the types of Liver Cancer Surgery?

There are two primary surgical approaches used to treat liver cancer:

Liver Resection (Partial Hepatectomy)

In this procedure, the surgeon removes the part of the liver that contains the tumour. This is only possible if the remaining liver is healthy enough to maintain normal function.

Types of liver resections include:

  • Right Hepatectomy: Removal of the right lobe of the liver.
  • Left Hepatectomy: Removal of the left lobe of the liver.
  • Central Hepatectomy: Removal of the central part of the liver, preserving parts of both lobes. This procedure is technically complex but allows for maximal preservation of healthy liver tissue.

Liver Transplant

If the cancer meets specific criteria (such as the Milan criteria, used to select suitable transplant candidates), the whole liver can be surgically taken out and replaced with a healthy liver from a donor. Doctors often consider this approach when liver damage or cirrhosis makes resection unfeasible.

What are the different approaches to perform Liver Surgery?

Liver cancer operations can be performed via the traditional open surgery, where a long cut is made in the abdomen to allow the surgeons to assess the liver.

Nowadays, due to the advancements made in instrumentations and surgical techniques, laparoscopic approach can also be considered. This is when surgeons perform the surgery through a few small holes. Recovery from laparoscopic surgery is much faster, due to the smaller wounds.

When is surgery for Liver Cancer recommended?

Surgery is not suitable for every liver cancer patient. It is typically recommended when:

  • The tumour is confined to the liver and has not spread to other organs
  • The cancer is found early and is limited in size and number
  • Liver function is adequate
  • The patient is physically fit to undergo a major operation

Procedure for Liver Cancer Surgery

Before

Prior to surgery, your care team will conduct:

  • Liver function tests to check how well your liver is functioning
  • Imaging scans (CT, MRI, or PET) to locate tumours and evaluate surgical options
  • Cardiac and general health evaluations to ensure you’re fit for anaesthesia and recovery

Your doctor may require that you stop certain medications, adjust your diet, and avoid alcohol in the days leading up to the operation.

During

Under general anaesthesia, the surgical team will remove the affected part of the liver. In a liver resection, this involves cutting away the tumour along with a section of healthy tissue. In a transplant, the entire liver is replaced with a donor organ and then connected to the recipient’s blood vessels and bile ducts.

Surgery time varies, but most cases take between 4 and 8 hours.

After

Recovery begins in the hospital, often in an intensive care setting. You’ll be monitored closely for:

  • Bleeding or fluid buildup
  • Liver function performance
  • Infection or bile leakage

Pain management, wound care, and gradual reintroduction of diet and activity are part of the routine. Most patients are hospitalised for about 7 to 14 days, with transplant recipients requiring more extended stays and lifelong anti-rejection medication.

Risk Factors for Liver Cancer

Understanding what increases your risk for liver cancer can help with early detection and prevention. While some risk factors are genetic, others are related to lifestyle or pre-existing health conditions. These include:

  • Chronic hepatitis B or C infections
  • Cirrhosis from alcohol-related liver disease or other causes
  • Non-alcoholic fatty liver disease (NAFLD)
  • Exposure to aflatoxins, toxins from mould found in some grains and nuts
  • Family history of liver cancer
  • Diabetes and obesity, which contribute to fatty liver and liver inflammation

Cost of Liver Cancer Surgery

The cost of liver cancer surgery in Singapore depends on the type of procedure chosen. Quoting from the Ministry of Health Doctors Fee Benchmark, the doctors’ professional fees are as follows:

For partial liver resection

Based on the Ministry of Health (MOH) of Singapore’s historical bill data, surgeon fees typically range from S$18,800 to S$33,600 (excluding GST).

For liver transplant

Due to its complexity and post-op care needs, transplant costs are significantly higher and can range well beyond S$22,400.

These figures reflect only the surgeons’ fees. The final hospital bill will also depend on:

  • Your choice of hospital
  • Length of hospital stay and recovery needs
  • Charges for anaesthesia, diagnostic tests, or other services
  • Your insurance plan’s co-payment, deductible coverage, and claims limits

Procedures are Medisave-claimable, helping you cover part of the cost. Additional support may be available through your integrated shield plan or private insurance. For a cost estimate tailored to your situation, speak with your hospital’s financial counsellor or care team.

Liver Cancer Surgery FAQs

Eligibility depends on the size, number, and location of tumours, overall liver health, and whether the cancer has spread. Pre-surgical evaluations will help determine your suitability.

Up to 70% of a healthy liver can be removed, provided the remaining portion is sufficient to maintain normal function. This is less in patients with cirrhosis or fatty liver disease.

Yes. The liver is capable of regeneration. Within weeks to months, the remaining liver can regrow to compensate for the lost volume.

You’ll need to undergo blood tests and imaging, adjust your medications, and possibly fast before surgery. Quitting alcohol and smoking can improve your surgical outcome and recovery.

Watch for:

  • Persistent fever
  • Yellowing of the skin (jaundice)
  • Abdominal swelling or severe pain
  • Discharge or redness at the surgical site
  • Difficulty breathing or changes in mental alertness

See a doctor if any of these symptoms appear.

Follow-up includes imaging every 3 to 6 months for the first two years, followed by annual imaging thereafter. These scans monitor for tumour recurrence or changes in liver health.

The prognosis depends on the stage of cancer and underlying liver condition. When liver cancer is detected early and surgically removed or treated with a transplant, 5-year survival rates can be up to 70% in some cases.

Consult Our Liver Cancer Surgeons

At Nexus Surgical, our skilled surgeons offer comprehensive liver cancer treatment. If you’ve been diagnosed or are seeking a second opinion about your treatment opinions, we’re here to help.

Consult Our Doctors

colorectal cancer specialists

Dr Jane Tan Jye Yng

Colorectal & General Surgeon

Lim Khong Hee

Dr Lim Khong Hee

Upper Gastrointestinal, Bariatric & General Surgeon

Cost & Financing

Nexus Surgical provides comprehensive financial services to ensure a seamless and pleasant experience. 

Contact Us

Mount Alvernia Hospital Medical Centre A

(65) 6353 4855

Mount Elizabeth Medical Centre

(65) 6235 8633

Mount Elizabeth Novena Specialist Centre

(65) 6570 2720

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Our clinics will be closed from 16 – 18 Feb for CNY

Notice on Clinic Relocation

Our clinic at Mt Alvernia Medical Centre A will be relocating from #06-05 to #03-03 (within the same building) on Friday, 26 Sep afternoon.

Our telephone line 6353 4855 will be temporarily unavailable from 12:00pm – 6:00pm on 26 September. During this period, you may reach out to our other clinics for assistance:

We will begin operations at our new premises (#03-03) from Tuesday, 30 Sep onwards.

We look forward to serving you at our new clinic!

Nexus Surgical clinics at Mt Elizabeth Novena Specialist Centre, Gleneagles Medical Centre, Parkway East Medical Centre and Mt Alvernia Medical Centre will be closed on 28 January 2025 for Lunar New Year celebrations, while our clinic at Mt Elizabeth Orchard Medical Centre remains open from 0900-1300 hours on 28 January 2025.

Please leave a message in our voice mails and we will respond to you as soon as we can when we resume our clinics on 31 January 2025. If you require any urgent assistance, kindly go to the Urgent Care Centre of any hospitals or contact your doctor through the Emergency Answering Service. Our team at Nexus Surgical would like to take this opportunity to wish you and your loved ones a Happy & Prosperous Lunar New Year with good health in the Year of the Snake!

Nexus Surgical will be away from 17 to 20 October 2024 for our Annual Company Retreat. The aim of our retreat is to review and to recharge, so that we may serve you better. 

Our clinics at Mount Elizabeth Orchard, Mount Elizabeth Novena, Mount Alvernia and Parkway East hospitals will therefore be closed during this period. In the meantime, if you require any urgent assistance, kindly contact us through our Answering Service at +65 6333 5550.

We thank you for your understanding and patience for any inconvenience.