Surgery for Gallbladder Cancer

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Surgery for Gallbladder Cancer

When gallbladder cancer is caught at a stage where surgery is possible, outcomes can be better than many patients expect.

At Nexus Surgical, our gallbladder surgeons provide the full range of procedures, from simple cholecystectomy to complex extended resections.

When is Surgery for Gallbladder Cancer recommended?

Surgery for gallbladder cancer.

Surgery is recommended when the cancer is localised, but whether surgery is suitable depends on several factors:

  • The stage of the cancer at diagnosis
  • Whether the tumour has spread to nearby structures such as the liver, bile duct, or lymph nodes
  • Your overall health and fitness for a general anaesthetic
  • The results of imaging and staging investigations

In early-stage gallbladder cancer (stage I), surgery alone may be sufficient. In later stages, surgery may be combined with chemotherapy or radiotherapy as part of a broader treatment plan. 

Not all cases of gallbladder cancer are operable at the time of diagnosis, and the decision to operate will be based on a full review of your staging investigations and overall health.

What are the types of Gallbladder Cancer Surgery?

The type of gallbladder surgery recommended depends on the stage and extent of the cancer. Our gallbladder surgeons manage both straightforward and complex gallbladder cancer cases.

Simple Cholecystectomy

A simple cholecystectomy involves removing the gallbladder alone. This approach is appropriate for very early-stage gallbladder cancer (stage IA), where the tumour is confined to the inner lining of the gallbladder and has not grown into the deeper muscle layer.

The procedure is typically performed laparoscopically (using keyhole techniques), which means smaller incisions, less post-operative discomfort, and a faster recovery compared with open surgery.

Extended Cholecystectomy

For cancer that has grown beyond the innermost layer of the gallbladder (stage IB and above), a more extensive operation is required. An extended cholecystectomy involves removing the gallbladder and a margin of liver tissue immediately adjacent to it, as well as the regional lymph nodes in the area.

Depending on how far the cancer has spread, additional structures may need to be removed, including part of the bile duct or nearby portions of the bowel. This is a more complex procedure, and can be performed either laparoscopically or with open surgery.

Additional Surgery After Incidental Cancer Diagnosis

Gallbladder cancer is sometimes discovered unexpectedly after a routine cholecystectomy carried out for gallstones or other benign conditions. This is referred to as incidental gallbladder cancer.

When this occurs, the pathology report from the removed gallbladder determines whether further surgery is needed. If the cancer is confined to the innermost layer (pT1a), no additional surgery is generally required. 

For deeper tumours (pT1b and above), a second operation to remove additional tissue is typically recommended to improve the likelihood of complete cancer clearance.

Procedure for Gallbladder Cancer Surgery

Once the appropriate procedure has been identified, here is what to expect from start to finish.

Before

  • Blood tests to check your overall health and organ function.
  • Imaging such as a computed tomography (CT) scan or magnetic resonance imaging (MRI).
  • In some cases, a positron emission tomography (PET) scan to assess whether the cancer has spread to other parts of the body.
  • A review of any medications that need to be paused before the procedure.
  • A meeting with your anaesthetist to discuss the type of anaesthesia planned and address any concerns.
  • Fasting instructions in the period leading up to surgery.

During

  • You will be placed under general anaesthesia before the procedure begins.
  • Your surgeon will make either keyhole incisions (laparoscopic) or a single open incision, depending on the procedure planned.
  • Your surgeon will remove the gallbladder, along with any additional tissue as required by the stage of the cancer.
  • If an extended procedure is being performed, your surgeon will remove nearby lymph nodes and send them for laboratory analysis.
  • Where relevant, the surgical team will take a small tissue sample during surgery to check the margins before the procedure is completed

After

  • You will be moved to a recovery area while the anaesthesia wears off and your recovery is monitored.
  • Pain relief will be managed by the nursing team in the hours and days following surgery.
  • You will be encouraged to begin moving as soon as it is safe to do so, to reduce the risk of blood clots.
  • Drain tubes may be in place temporarily if excess fluid drainage is required following an extended procedure.
  • Your surgical team will review your progress before discharge and discuss your follow-up schedule.
  • A follow-up appointment will be arranged to review the laboratory results and determine whether any further treatment is needed.

Risks and possible complications of Gallbladder Cancer Surgery

 

As with any major surgery, gallbladder cancer surgery can carry a degree of risk. Your surgeon will discuss these with you in detail.

General surgical risks (all procedures):

  • Bleeding during or after surgery
  • Infection at the wound site or internally
  • Bile leak, which may require further intervention
  • Blood clots in the legs or lungs (deep vein thrombosis or pulmonary embolism)
  • Reactions to anaesthesia
  • Slower digestion or nausea after eating

Additional risks (extended cholecystectomy):

  • Temporary liver dysfunction following liver resection
  • Complications related to bile duct reconstruction, where required

Cost of Gallbladder Cancer Surgery in Singapore

The cost of gallbladder cancer surgery in Singapore varies depending on the complexity of the procedure, the length of your hospital stay, and any additional treatments required.

Patients with MediSave and MediShield Life coverage may be eligible to use these to offset a portion of the costs. If you hold a private integrated shield plan, coverage will depend on your insurer and plan terms. You can find more information about financing options here.

Gallbladder Cancer Surgery FAQs

No. Surgery is the primary treatment when the cancer has not spread beyond a point where removal is possible. When it has spread widely, the focus shifts to other treatments such as chemotherapy or care aimed at managing symptoms and quality of life.

It depends on how deeply the cancer has grown into the gallbladder wall. Cancers that have not grown beyond the innermost layer (pT1a) do not require further surgery. For cancers staged deeper than this, surgeons typically recommend a second operation to remove additional tissue around the original site.

It varies by procedure. Keyhole surgery generally allows a faster recovery than open surgery. Individual factors such as age, overall health, and whether any complications arise, also affect the timeline. Your surgeon will give you a clear picture of what to expect before you leave the hospital.

Not always. Where the cancer was found at a more advanced stage, your surgeon may recommend adjuvant (post-operative) chemotherapy to reduce the risk of it returning. This decision is based on your surgical results and overall health.

Yes, recurrence is possible. The risk depends largely on the stage of the cancer at the time of surgery. Regular follow-up appointments, including imaging and blood tests, help detect any changes early.

Speak to a Gallbladder Surgeon in Singapore

If you or someone you care for has been diagnosed with gallbladder cancer, taking the time to understand your surgical options is an important first step. Our gallbladder surgeons in Singapore are available to answer your questions and guide you through what to expect.

There is no obligation. A consultation is simply an opportunity to get clear, honest information so you can make a decision about your care.

Contact Nexus Surgical to arrange a consultation.

Consult Our Doctors

colorectal cancer specialists

Dr Jane Tan Jye Yng

Colorectal & General Surgeon

Lim Khong Hee

Dr Lim Khong Hee

Upper Gastrointestinal, Bariatric & General Surgeon

Cost & Financing

Nexus Surgical provides comprehensive financial services to ensure a seamless and pleasant experience. 

Contact Us

Mount Alvernia Hospital Medical Centre A

(65) 6353 4855

Mount Elizabeth Medical Centre

(65) 6235 8633

Mount Elizabeth Novena Specialist Centre

(65) 6570 2720

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Our clinics will be closed from 16 – 18 Feb for CNY

Notice on Clinic Relocation

Our clinic at Mt Alvernia Medical Centre A will be relocating from #06-05 to #03-03 (within the same building) on Friday, 26 Sep afternoon.

Our telephone line 6353 4855 will be temporarily unavailable from 12:00pm – 6:00pm on 26 September. During this period, you may reach out to our other clinics for assistance:

We will begin operations at our new premises (#03-03) from Tuesday, 30 Sep onwards.

We look forward to serving you at our new clinic!

Nexus Surgical clinics at Mt Elizabeth Novena Specialist Centre, Gleneagles Medical Centre, Parkway East Medical Centre and Mt Alvernia Medical Centre will be closed on 28 January 2025 for Lunar New Year celebrations, while our clinic at Mt Elizabeth Orchard Medical Centre remains open from 0900-1300 hours on 28 January 2025.

Please leave a message in our voice mails and we will respond to you as soon as we can when we resume our clinics on 31 January 2025. If you require any urgent assistance, kindly go to the Urgent Care Centre of any hospitals or contact your doctor through the Emergency Answering Service. Our team at Nexus Surgical would like to take this opportunity to wish you and your loved ones a Happy & Prosperous Lunar New Year with good health in the Year of the Snake!

Nexus Surgical will be away from 17 to 20 October 2024 for our Annual Company Retreat. The aim of our retreat is to review and to recharge, so that we may serve you better. 

Our clinics at Mount Elizabeth Orchard, Mount Elizabeth Novena, Mount Alvernia and Parkway East hospitals will therefore be closed during this period. In the meantime, if you require any urgent assistance, kindly contact us through our Answering Service at +65 6333 5550.

We thank you for your understanding and patience for any inconvenience.